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Final

Lecture 5 - EXAM VERSION.docx

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Department
Biology
Course
BIO3153
Professor
Michael Jonz
Semester
Fall

Description
Lecture 5EXAM VERSIONNovember2012333 PM EXTRACELLULAR CONTROLTotal Cell MassTotal cell masssize of organorganismoCell divisioncell deathtotal cell numbertotal cell massoSize dependent on cell growthIncrease total cell mass by getting more cells or making them biggerWhat controls divisions and sizes of cells Controlling divisions and deaths total cell mass dependent onoGrowth factors increase synthesis decrease degradationoMitogen promotes progression through cell cycle and cell divisionoSurvival factors decrease apoptosis Growth FactorsNeeded for growth of animal cellsIncrease synthesis Increases myc GRP decrease degradationExtracellular signalling proteins GF chemical stimulus signal binds to cell surface receptor induces intracellular pathwayExtracellular bindingtransmembrane domainintrinsic enzyme activity autophosphorylationoAct through receptor tyrosine kinase enzyme link receptorsoBindinggrowth factor to receptor brings 2 kinase domains togetheroLigand dimer binding
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