BPS 2110 Study Guide - Midterm Guide: Reagent, Passive Transport, Hypoactive Sexual Desire Disorder

• School: University of Ottawa
• Department: Biopharmaceutical sciences
• Course: BPS 2110
• Professor: Robert Ben

Document Summary

Lecture 1 critical thinking & evidence-based science. Investigation for its patient assistance program, drug prices & distribution- buy not build model. Buy small drug developers and then hike $ on drugs developed by that company. Slash research funds for new drugs (3% of sales vs. 15-20% normal for other drug groups). Philidor whose sales were 6. 8% of valeant"s total revenue, told employees to change codes- appeared that. Dr. required or pt. desired valeant"s brand-name drugs. Us 2 largest pharmacies: cvs health & express scripts ended interactions with valeant (business practice) Addyi : 1st drug approved by fda for hypoactive sexual desire disorder. Serotonin 1a agonist: lower anxiety, cheerful, joy (antidepressant) Serotonin 2a antagonist: lower anxiety, hypoactive sexual desire. 3 randomized phase 3, double-blind; pre-menopausal women with mean age of 36 years. Consistently demonstrated a statistically significant difference over placebo on 3 endpoints, including sexual desire, distress from the loss of sexual desire and frequency of satisfying sex.