BPS2110- Final Exam Guide - Comprehensive Notes for the exam ( 114 pages long!)

• School: University of Ottawa
• Department: Biopharmaceutical sciences
• Course: BPS 2110
• Professor: Robert Ben

Document Summary

The pharmaceutical industry: multi-billion dollar industry, highly regulated, more than any other industry, fda, health canada, us takes (cid:1005)/(cid:1006) of i(cid:374)dustry, e(cid:448)eryo(cid:374)e else (cid:272)opies us fda (cid:373)ore i(cid:373)pt. The pharmaceutical industry: multi-billion-dollar industry, highly regulated, more than any other industry, fda, health canada, us takes (cid:1005)/(cid:1006) of i(cid:374)dustry, e(cid:448)eryo(cid:374)e else (cid:272)opies us fda (cid:373)ore i(cid:373)pt. Schizophrenia: black = small molecule, blue = antibody, green = recombinant protein, almost all of these drugs are chronic. Lots of ways that drugs and biological molecules interact: cannot predict beforehand, do(cid:374)"t (cid:449)a(cid:374)t to just test (cid:448)ersio(cid:374)s of the sa(cid:373)e (cid:272)o(cid:373)pound. Sponge was extinct on the 3rd try: driven extinct by the desire to make it a drug, no(cid:449) this (cid:272)ould (cid:374)e(cid:448)er (cid:271)e a drug (cid:271)(cid:272) (cid:449)e do(cid:374)"t e(cid:448)e(cid:374) ha(cid:448)e the ge(cid:374)eti(cid:272) i(cid:374)fo to repli(cid:272)ate it. Acyclovir resembles guanine: cold sore meds, red portion is kept again. Fillers: ensure consistent dosing, disintegrants, (cid:862)blo(cid:449)s(cid:863) the pill apart in the stomach.