CHM 1321 Study Guide - Sodium Hydroxide, Magnesium Bromide, Diethyl Ether
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CHM 1321 Full Course Notes
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Experiment #6: preparation of benzoic acid using a grignard reagent. To synthesize benzoic acid using a gringnard reagent. Grignard reagents, also known as organometallic compounds, are made up of an organic component and metal component, usually a transition element that can combine to form c-c bonds. The general structure of such compounds is rmgx. R represents an alkyl, a vinyl, or an aryl, and x represents any halogen. During grignard reactions the mg in the organo-halide compound becomes oxidized, changing oxidation states from. As well the alpha carbon of the grignard reagent becomes negatively charged, transforming it into a good nucleophile. Grignard reagents are even more useful as they have the ability to undergo nucleophilic displacements with molecules that have polarized double bonds, such as aldehydes, ketones and esters. Adding a grignard reagent to an aldehyde, ketone, or ester produces a secondary or tertiary alcohol.