MIC 4124 Study Guide - Midterm Guide: Chromosome, Antigen, Immunocompetence

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Long, slender, coiled (due to axial fibrils) gram-negative bacteria. Cell structure and motility is due to axial fibrils. In literature, they are referred to as axial filaments, axial fibrils, or periplasmic flagella. It is a flagellum on the inside of the periplasm. Examples of diseases in human caused by spirochetes. They are symbionts of cows and other ruminants. The live in the stomach and break down cellulose for the host. They have a remarkable ability to invade, disseminate, and persist in their hosts. Other pathogens are normal oral and genital flora or free-living. It is attached at one point and winds its way through. Note that it doesn"t run all the way around the cylinder. Spirocehtes penetrate intact mucous membranes through lesions in the membranes or through arthropod-borne infections (e. g. : ticks) Treponema doesn"t need a vector to gain access. Spirochete-specific motility is a key factor in invasion and dissemination because of the ability to move through viscous substances.

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