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Midterm

PHA3112 Midterm: practice questions lecture 1 study guide

by OneClass871445 , Winter 2017
8 Pages
74 Views
Winter 2017

Department
Pharmacology
Course Code
PHA 3112
Professor
Frank Feiner
Study Guide
Midterm

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Lecture 1 practice questions
1. A drug is defined as…
2. Pharmacology is defined as…
3. Therapeutics is defined as…
4. What are the ‘big 3’ ideal properties of the “perfect drug”?
5. What are the 3 factors that determine the intensity of drug response?
6. What are the 4 phases of pharmacokinetics? (hint: ADME)
7. With regards to IV administration of a drug, are there any barriers to absorption?
8. What is the absorption pattern of IM administration?
9. Certain barriers can affect drug distribution, like the blood brain barrier. What prevents drugs
from leaving the blood and reaching the brain?
10. What kind of drugs can cross the blood brain barrier?
11. What is the most important blood protein that drugs bind reversibly with?
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12. What blood protein prohibits drugs from reaching their site of action when bound to?
13. The kidney is unable to excrete what kind of drugs?
14. What are the 6 possible consequences of therapeutic significance?
15. What are the drug metabolizing enzyme in the liver?
16. A drug may be a :
17. Which organ accounts for the majority of drug excretion?
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18. What is the minimum effective concentration defined as?
19. What is the therapeutic range of a drug defined as?
20. What is the half-life of a drug defined as?
21. Hepatic microsomal enzymes _______________
22. What would cause the duration and intensity of a drug response to increase?
23. What is the major route for volatile anesthetics?
24. Along with the liver, the ___________ is a major organ of drug excretion
25. If renal failure occurs, what can happen to the drug response?
26. Where does the therapeutic range of a drug lie?
27. What kind of drugs are relatively easy to use safely?
28. Describe the actions of an agonist
29. Describe the actions of an antagonist
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Description
Lecture 1 practice questions 1. A drug is defined as… 2. Pharmacology is defined as… 3. Therapeutics is defined as… 4. What are the ‘big 3’ ideal properties of the “perfect drug”? 5. What are the 3 factors that determine the intensity of drug response? 6. What are the 4 phases of pharmacokinetics? (hint: ADME) 7. With regards to IV administration of a drug, are there any barriers to absorption? 8. What is the absorption pattern of IM administration? 9. Certain barriers can affect drug distribution, like the blood brain barrier. What prevents drugs from leaving the blood and reaching the brain? 10. What kind of drugs can cross the blood brain barrier? 11. What is the most important blood protein that drugs bind reversibly with? 12. What blood protein prohibits drugs from reaching their site of action when bound to? 13. The kidney is unable to excrete what kind of drugs? 14. What are the 6 possible consequences of therapeutic significance? 15. What are the drug metabolizing enzyme in the liver? 16. A drug may be a : 17. Which organ accounts for the majority of drug excretion? 18. What is the minimum effective concentration defined as? 19. What is the therapeutic range of a drug defined as? 20. What is the half-life of a drug defined as? 21. Hepatic microsomal enzymes _______________ 22. What would cause the duration and intensity of a drug response to increase? 23. What is the major route for volatile anesthetics? 24. Along with the liver, the ___________ is a major organ of drug excretion 25. If renal failure occurs, what can happen to the drug response? 26. Where does the therapeutic range of a drug lie? 27. What kind of drugs are relatively easy to use safely? 28. Describe the actions of an agonist 29. Describe the actions of an antagonist 30. Describe the actions of a partial agonist 31. Describe the actions of an inverse agonist 32. What is the ‘initial dose” and what is it used as? 33. What is ED50 defined as? 34. What is the dose where 50% of population is killed? 35. What is the therap
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