PHS 4300 Study Guide - Quiz Guide: Chemotherapy, Bone Pain, Embolus

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Affects blood & blood forming tissue such as bone marrow, spleen, etc. Leukocytosis- in response to an infection, the normal function of your body is to increase production of white blood cells. When leukocytosis persists that is when it is a red flag for leukemia. Causes: thought to be genetic, radiation, viruses, etc. Can be from a combination of factors and causes. Usually you have an abnormal stem cell then it gets into the circulation, they will grow to the point where they will be more prevalent than regular stem cells. Extramedullary hematopoiesis: causing the organs to enlarge (spleen, etc. ) Signs & symptoms: asymptomatic for a long time. Fatigue, headache, pain in the left side can be a red flag (could be the spleen). Accelerated stage: the # of blast cells increases, and normal cell #(cid:495)s start to decrease. Night sweats, weight loss, dyspnea, anemia can develop. Blast crisis: blast cells outnumber the functioning cells.