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Final

BIO315H5 Study Guide - Final Guide: Transcriptional Regulation, Apaf1, Protein Kinase B


Department
Biology
Course Code
BIO315H5
Professor
Hai- Ying Mary Cheng
Study Guide
Final

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LECTURE 21 – APOPTOSIS

 
 
o
o
o 
o
!" 
" #
o$
o%
 #&
necrosis#& "
 %#

 '"
 &(#
Importance of apoptosis
 )"
o#
* " 
#
 +
o),#-".(" ,
#
 /01
o&!
o"*
 -"#
Hallmarks of Apoptosis
 ).*2
o3* *#&
(* "*
#
o&4"
5"* &6)7
o&&6&$
 ),%

o,+
o$
 7
 8
9

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The role of Proteolyc cascade in apoptosis
 4#
o': "
 (#
 &".iniator execuoner 
 &",
 #(#
 ),,4
"
 &irreversible  self-amplifying
Caspase acvaon during apoptosis
#&; 
 
<#=
 
#&4#' >
#?
#) >
>#"
#',#),
,#
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DNA fragmentaon during Apoptosis (diagram to right)
 &,@
#?*#&

*"9AB>BB#
&,#C
**#' 
#)D"*#
Iniaon of the caspase cascade
 ""#&>"#
9 ),., 
#
o'",

o*&
,#&
o&&#
 &,"..
o3#3<
,#&
#&
",#"
#&#
= **"#&**
"#&**>#
# *""
# *@A#A
,#&","*'C
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