BIO206H5- Final Exam Guide - Comprehensive Notes for the exam ( 40 pages long!)
Document Summary
Inorganic ions: variety of organic ocmpounds, organelles (not all in cell, water, collectively displays the 5 characteristics of life, cells vary greatly in composition, size and function, central dogma is unifying principal that unites all life. Ionic bond: protein- mediated, newly synthesized, partially folded protein, chaperone proteins correctly folded protein (minimum energy confirmation, one polypeptide chain is sequestered by the chaperone, correctly folded protein is released when cap dissociates. Importance of folding: many consequences of misfolded proteins, loss of function, disease, entire protein-folding network has evolved to facilitate and/or catalyze. If there"s a lot, then there"s a higher chance that they will reattach: some leave blunt ends, no overhang, a lot more difficult to stick together. Strand: mrna transcript = sense, antisense rna (- strand) Bio206 lecture 10: tfiih phosphorylates ctd, tfiih, with help of mediator phosphorylates c terminal of rna polymerase.
