Lecture notes and notes from book (Fundamentals of Human Neuropsychology)

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Melissa Holmes

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ImagingtheBrainsActivity January-31-10 12:52PM Portrait:AngeloMosso { PositronEmissionTomography(PET) { Showshowbloodflowsinthebrain { AngeloMosso { Firsttoexaminechangesinbloodflowinrelationshiptomentalactivity { Measuredbloodflowinthebrainandbloodpressure(BP)simultaneously { Foundthatduringmentalactivitybloodflowincreasedinthebrain,butBPdidnotchange Slide3 K2]L2Z ]L[Z ]] { ElectricalRecording { Detectchangesintheelectricalactivityoftheneurons { BrainStimulation { Inducechangesintheelectricalactivityoftheneurons { X-RayImaging { Sensitivetothedensityofdifferentpartsofthebrain { DynamicImaging { Recordsandmanipulatesongoingchangesinbrainactivity @[email protected] ZL]Z}Z }]L2Z ]L[Zo ] o ]] { 1)Singlecellrecording { Anelectrodeisinsertedintothebrain,adjacenttoaneuron,theneuronsactivityis recorded { Mostcommonlydonewithanimals Slide6 { Manyindividualneuronscanberecordedsimultaneously { Canrecorda singleactionpotentialormanyactionpotentials { http:www.youtube.comwatch?v=mJJGZP9Dtq4 Slide7 { Theneuronalcode: { Neuronsexhibitdifferentfiringpatternsindifferentspecies,indifferentcircumstancesand duringdifferentbehaviors { Informationcanbeencodedinseveralways Timecode(stimuluson=firing;stimulusoff=nofiring) Eventcode(firingonlyatonsetandoffsetofstimulus) ^LLZ] }_)L }]]L2~Zo]LZ:]L ZZ: Z Slide8 { Brainusescodestorepresentinformation Slide9 { ,}Z]Z^ }]L2_}lZ9 { Neuronshaveanarrowbehavioralrepertory,respondtoonlyonetypeofsensoryeventor behavior { Nearbyneuronshavedifferentrepertories,suggestinginteraction { Well-learnedbehavior=fewneurons { Newlylearnedbehavior=widespreadactivity 2)Electroencephalographic(EEG)Recording { }Zo ] o}L]oZ}^]LZ_]LZ]L { Asummationofgradedpotentials { Generator { Neuronsthatproducetherhythmicalsignal { EEGusedfor { Sleepstudies { Monitoringthedepthofanaesthesia www.notesolution.com
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