BIOB10H3 Study Guide - Midterm Guide: Mitochondrial Fission, Mitochondrial Matrix, Mitochondrial Fusion
Document Summary
Mitochondrial fission: division of mitochondria within cell. Mitochondrial fusion: fusion of mitochondria within cell. Balance between fission & fusion dictates mitochondrial number & length to (cid:373)eet (cid:272)ell"s e(cid:374)e(cid:396)g(cid:455) (cid:396)e(cid:395)ui(cid:396)e(cid:373)e(cid:374)t. Mitochondrial fission: induced by contact with thin tubules from the er, which encircle the mitochondrion like a noose. Completed through the action of soluble cytosolic proteins recruited to the outer surface of the mitochondrion. Serves as the outer boundary of the organelle. Has diverse number of proteins that function as enzymes. Several large protein channels: porins (cid:894) -pleated sheets, allow passage of large number of molecules, respond to condition within the cell) *gfp (green fluorescent protein) : has b-pleated sheet structure critical to its function but not acting as a channel. Almost no cholesterol rich in cardiolipin (type of phospholipid) Very impermeable to molecules, but has many channels & pumps act as a firm barrier. Gel-like consistency from high conc. of proteins. Mitochondrial dna encodes ~37 genes in humans.
