[BIOB11H3] - Final Exam Guide - Everything you need to know! (192 pages long)
Document Summary
Nuclear pore complex: highly selective, bidirectional transporter for cargoes. Include inner membrane proteins and all the proteins in the nucleoplasm; gateway that regulates flow of macromolecules b/w cell nucleus. Nuclear matrix: the network of fibres found throughout the inside of a cell nucleus. Chromatin: chromosomes, present as highly extended nucleoprotein fibers. Nuclear envelope: double lipid bilayer membrane which surrounds the genetic material and nucleolus in eukaryotic cells; inner nuclear membrane & outer nuclear membrane. Nucleoporins: family of proteins which are the building blocks of the npc. Nuclear localization signal: stretch of aa near c-terminus, enables protein to pass through nuclear pores and enter the nucleus. Importins: type of karyopherin that transports protein molecules into the nucleus by binding to specific recognition sequences, called nuclear localization signals (nls) Exportins: transports proteins out of the nucleus. Histones: small proteins that possess a high content of arg and lys. Nucleosomes: dna and histones in repeating subunits.
