Study Guides (256,446)
CA (124,649)
UTSC (8,077)
BIOB11H3 (47)
Midterm

b11 midterm

10 Pages
151 Views

Department
Biological Sciences
Course Code
BIOB11H3
Professor
Shelley A.Brunt

This preview shows pages 1-3. Sign up to view the full 10 pages of the document.
BGYB11 Midterm 1
1. Mendels law of independent assortment states that
segregation of an allelic pair for one trait had no effect on the segregation of alleles for another trait.
2. How many chromosomes would a sexually reproducing organism with 6 chromosomes in generation 1 have in
generation 4 if the normal reductional division takes place in meiosis?
4
3. If pollen from a plant that is hetero for a mutant allele is used to fertilize another plant that is null for the allele,
what is the expected ratio of progeny?
half offspring are heterozygotes
4. If primary non-disjunction occurs at spermatogenesis:
half gametes have an extra chromosome
5. During the first meiotic division, HOMOLOGS segregate one another, second meiotic division, the SISTER
CHROMATIDS segregate from one another.
6. Consider a single autosome (e.g. chromosome 4) that you have. Which statement is always true?
a. I received more of chromosome 4 DNA from my maternal grandparents than my paternal grandparents
b. I received 25% of my chromosome 4 DNA from each of my grandparents
c. I received either 0% or 50% of my chromosome 4 DNA from my paternal grandfather
d. I received either 50% or 100% of my chromosome 4 DNA from my maternal grandfather
e. None of the above
7. Suppose that you had two solutionns of DNA, one single stranded (ssDNA) and the other double stranded
(dsDNA). You take some of each and determine that UV light absorption by the single stranded sample is 50%
greater than that of the double stranded sample. What does this tell you about the relative concentrations of DNA
in the original samples?
a. the ssDNA is 0.5 times more concentrated than the dsDNA
b. the ssDNA is 2 times as concentrated as the dsDNA
c. the dsDNA is 0.5 times more concentrated than the ssDNA
d. the dsDNA is 2 times as concentrated as the ssDNA
e. the two samples have the same concentration
8. Consider two organisms with genomes of equal size. The GC content of the first is 40% while that of the second
is 33%. Which of the following statements is true?
a. the melting temperature of genome 1 is lower than that of genome 2
b. the melting temperature of genome 2 is lower than that of genome 1
c. the complexity of genome 1 is greater than that of genome 2
d. both a and c
e. both b and c
9. Based on Chargaff’s observations on base composition of DNA, which of the following mathematical statements
are true of every double stranded DNA sample?
1
www.notesolution.com
a. [A]+ [C] = 100 – [T]
b. [T] = [C]-[A]
c. [A] + [C] = [G] + [A]
d. [A] + [T] = [C] + [G]
e. both c and d
10. Which of the following factors influence DNA reannealing/hybridization?
a. temperature
b. DNA fragment length
c. ionic strength
d. both a and c
e. all of the above
11. Which of the following statements about transposable elements are true?
a. after integrating into the host genome, direct repeats are formed as a result of repair synthesis
b. an active transposon encodes an enzyme known as kinase, an enzyme that cleaves the DNA and inserts the
transposon into the recipient site
c. some transposons move by a cut and paste mechanism that
involves an RNA intermediate
d. both a and b
e. both a and c
12. The reannealing of the DNA of a higher eukaryotic organism is
shown in the figure. Which fraction of the genome (denoted by
boxes A, B, C) would gene for ribosomal RNA be found?
a. A
b. B
c. C
d. it depends on the organism
13. The ends of linear eukaryotic chromosomes are referred to as
a. centromeres
b. centrosomes
c. centrioles
d. acromeres
e. telomeres
14. The following recombination frequencies were found for four genes, A, B, C, and D, on the same chromosome:
between genes A and B – 35%, between genes C and D10%, between A and D8%, between genes C and B
16%, between genes C and A19%, and between genes B and D27%. What was the order of the genes on the
chromosome?
a. ABCD
b. BACD
c. ACDB
d. ADCB
e. CADB
2
www.notesolution.com
15. Which of the genes in question 14 above are likely to have the most crossing over between them?
a. A and Bd. B and C
b. A and Ce. C and D
c. A and D
16. Which of the following techniques could be used to determine which chromosome contains a cloned gene of
interest (your favourite gene)?
a. in situ hybridization
b. reannealing experiment c. RLFP analysis
d. spectrophotometry e. none of the above
17. Unequal crossing over
a. leads to trisomy 21 or Down’s syndrome
b. leads to gametes which may have either duplicated genes or deleted genes
c. is a mechanism of rapid genome evolution
d. both b and c
e. all of the above
18. An example of a polymorphism is
a. a cDNA
b. an RFLP
c. a reverse transcriptase
d. a transpoase
e. none of the above
19. Genetic mapping involves
a. an analysis of the sequences of many clones representing an entire chromosome
b. the use of techniques such as gene closing and sequencing
c. an analysis of segregation of visible traits in the offspring of a specific genetic cross
d. both a and b
e. all of the above
20. The use of computational methods to analyze and organise large sequences datasets is known as:
a. computational genomics
b. biochemical genetics
c. biometrics
d. contig analysis
e. bioinformatics
21. Relatedness between individuals can be determined by RFLP
analysis. Suppose that the DNA from six individuals was
analyzed in this way. From the patterns shown, what can you
conclude about the relatedness of the samples? Note 1=2 > 4
>>>5 means that 1 and 2 are very related, that they are less
related to sample 4 and that these samples are distantly related to
sample 5.
a. 1 = 2 = 3 = 4
3
www.notesolution.com

Loved by over 2.2 million students

Over 90% improved by at least one letter grade.

Leah — University of Toronto

OneClass has been such a huge help in my studies at UofT especially since I am a transfer student. OneClass is the study buddy I never had before and definitely gives me the extra push to get from a B to an A!

Leah — University of Toronto
Saarim — University of Michigan

Balancing social life With academics can be difficult, that is why I'm so glad that OneClass is out there where I can find the top notes for all of my classes. Now I can be the all-star student I want to be.

Saarim — University of Michigan
Jenna — University of Wisconsin

As a college student living on a college budget, I love how easy it is to earn gift cards just by submitting my notes.

Jenna — University of Wisconsin
Anne — University of California

OneClass has allowed me to catch up with my most difficult course! #lifesaver

Anne — University of California
Description
1 BGYB11 Midterm 1 1. Mendels law of independent assortment states that segregation of an allelic pair for one trait had no effect on the segregation of alleles for another trait. 2. How many chromosomes would a sexually reproducing organism with 6 chromosomes in generation 1 have in generation 4 if the normal reductional division takes place in meiosis? 4 3. If pollen from a plant that is hetero for a mutant allele is used to fertilize another plant that is null for the allele, what is the expected ratio of progeny? half offspring are heterozygotes 4. If primary non-disjunction occurs at spermatogenesis: half gametes have an extra chromosome 5. During the first meiotic division, HOMOLOGS segregate one another, second meiotic division, the SISTER CHROMATIDS segregate from one another. 6. Consider a single autosome (e.g. chromosome 4) that you have. Which statement is always true? a. I received more of chromosome 4 DNA from my maternal grandparents than my paternal grandparents b. I received 25% of my chromosome 4 DNA from each of my grandparents c. I received either 0% or 50% of my chromosome 4 DNA from my paternal grandfather d. I received either 50% or 100% of my chromosome 4 DNA from my maternal grandfather e. None of the above 7. Suppose that you had two solutionns of DNA, one single stranded (ssDNA) and the other double stranded (dsDNA). You take some of each and determine that UV light absorption by the single stranded sample is 50% greater than that of the double stranded sample. What does this tell you about the relative concentrations of DNA in the original samples? a. the ssDNA is 0.5 times more concentrated than the dsDNA b. the ssDNA is 2 times as concentrated as the dsDNA c. the dsDNA is 0.5 times more concentrated than the ssDNA d. the dsDNA is 2 times as concentrated as the ssDNA e. the two samples have the same concentration 8. Consider two organisms with genomes of equal size. The GC content of the first is 40% while that of the second is 33%. Which of the following statements is true? a. the melting temperature of genome 1 is lower than that of genome 2 b. the melting temperature of genome 2 is lower than that of genome 1 c. the complexity of genome 1 is greater than that of genome 2 d. both a and c e. both b and c 9. Based on Chargaffs observations on base composition of DNA, which of the following mathematical statements are true of every double stranded DNA sample? www.notesolution.com
More Less
Unlock Document


Only pages 1-3 are available for preview. Some parts have been intentionally blurred.

Unlock Document
You're Reading a Preview

Unlock to view full version

Unlock Document

Log In


OR

Don't have an account?

Join OneClass

Access over 10 million pages of study
documents for 1.3 million courses.

Sign up

Join to view


OR

By registering, I agree to the Terms and Privacy Policies
Already have an account?
Just a few more details

So we can recommend you notes for your school.

Reset Password

Please enter below the email address you registered with and we will send you a link to reset your password.

Add your courses

Get notes from the top students in your class.


Submit