BIOC21H3 Study Guide - Cytoskeleton, Sickle-Cell Disease, Spectrin

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44% out of total 45% formed elements of blood. Rare; is see a lot of basophils on slide, patient is dead. Central area: region of pallor; lighter staining; fewer protein. Transport of oxygen via haemoglobin protein to cells and tissues. One of very first cells on site of infection. Associated with allergic reactions, parasitic infections, and chronic inflammation. Have cell surface immunoglo- bins ige which bind to fc receptors. Light staining nucleus (differenti- ates into osteoblasts and macro- phages) Very active during viral infections; an increase in production of lymphocytes. Involved in controlling activity of mast cells same way as mast cells. Basophils and mast cells have different precursors so not the same. Specialized to exit bloodstream and attach foreign pathogen. Have lysosomes but not detected due to intensely eosinophilic staining granules. Basophilia: lots of basophils; patient is dead; when degranulates. , whole bloodstr- eam is effected; anaphaylatic to antigens. Capable of recirculating; can enter connective tissue or lymphatic vessels.

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