BIOC32H3 Study Guide - Midterm Guide: Dyskinesia, Dorsal Root Of Spinal Nerve, Neuroplasticity
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K+ leak channels c. i. 1. efflux of potassium resulting in negative interior c. ii. 2 k+ influx c. ii. 3. electrogenic refers to net movement of positive charge out of the cell (efflux) c. ii. 4. requires atp active transport c. iii. properties of the plasma membrane c. iii. 1. impermeability c. iii. 2. presence of voltage gated ion channels. 4. components of a synapse: axon, axon terminal b. i. mitochondrion b. ii. synaptic vesicles b. iii. synaptic cleft, post-synaptic neuron c. i. ion channels c. ii. receptors. 6. receptor activation initiates a downstream signalling cascade a. signal transduction a. i. signal amplification: different receptor types activate different signalling cascades c. general mechanism c. i. neurotransmitter binds to receptor c. ii. receptor activates g protein c. iii. G protein activates amplifying enzyme c. iv. amplifying enzyme activates second messengers c. v. second messengers stimulate the cellular response. 7. types of receptors a. ionotropic a. i. chemical / ligand gated ion channels a. ii. activated by nt a. iii. coupled to ion channels a. iv. fast postsynaptic response: g-protein coupled receptors (gpcr) b. i.
