BIOC32H3 Study Guide - Midterm Guide: Metabotropic Glutamate Receptor, Resting Potential, Glutamate Receptor
Document Summary
Each compartment is comprised of mixture of different electrolytes (salt), sugars, protein. 1) apply integrated approach: require for hypothesis, experimental design. Integrated approach: use different method to address a question. Hypothesis = to assume , needs to be logical and informed based on information available. Need to be testable, depends on technologies available. Non testable hypothesis: consist variable which cannot be quantified. Experimental design: important to choose a correct system. Disadvantages: circuit not intact, functioned measurement is less direct (not direct answer) Advantages: intact system compared to test tube design, reduced inter-species variability and cost. Subjects are exposed to same living environment (reduce inter-species variability) Advantages: most relevant to hypotheses, medically / scientifically most relevant. Disadvantages: consist variability of race, sex, age and lifestyle. E. g. different level of training in personnel / constant testing environment. # of replicates per group: are the statistical reliable / cost problems. Psychological bias: either from patient or experimenter, placebo or double-blind study are needed.
