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BIOC34H3 (46)

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Department
Biological Sciences
Course Code
BIOC34H3
Professor
Stephen Reid

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Lecture 7 Study Notes
Resistance: degree to which blood flow is hindered. 4 factors affecting vascular resistance:
Vessel radius: primary regulator of resistance. Greatest influence as to the power
of 4
oSmooth muscle regulates vessel radius by dilating or constricting the blood
vessel
Vessel length
Viscosity
oMeasure of friction b/n different fluid layers and also friction with the wall of
the blood vessel
oHaematocrit: percentage of blood volume occupied by cells
The more haematocrit you have, the greater viscosity
oIf temperature is increased, viscosity decreases (for ever degree, 2% decrease
in viscosity)
Laminar vs. Turbulent flow
oLaminar flow: blood moving smoothly in one direction moving forward. We
have this when healthy
oTurbulent flow: erratic flowing of blood. It is not healthy, but happens when
you have plaque build up or hardening of arteries
Poiseuilles Law: R = 8L / r4
oL = VESSEL LENGTH; n = Viscosity; r = Radius; R = Resistance
Total Peripheral Resistance: the combined resistance of all blood vessels in systematic
circulation.
Blood flow within systematic and pulmonary circuits is in parallel, not from one organ to
the next.
Parallel circuits decrease blood flow resistance.
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Description
Lecture 7 Study Notes Resistance: degree to which blood flow is hindered. 4 factors affecting vascular resistance: Vessel radius: primary regulator of resistance. Greatest influence as to the power of 4 o Smooth muscle regulates vessel radius by dilating or constricting the blood vessel Vessel length Viscosity o Measure of frictionn different fluid layers and also friction with the wall of the blood vessel o Haematocrit: percentage of blood volume occupied by cells The more haematocrit you have, the greater viscosity o If temperature is increased, viscosity decreases (for ever degree, 2% decrease in viscosity
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