study guide

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Biological Sciences
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Stephen Reid

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Lecture 5 Study Notes There are 3 factors that regulate Stroke volume 1. Force of ventricular contraction: slide 7 - 8 This occurs through sympathetic innervation o NE or NA act on the Beta cells of the heart, which activate Gs protein that transform ATP into Camp. (Alpha cells as negative feedback) o Camp then acts on PKA, which: Opens Calcium channels, allowing for Ca increase Acts together with increased Ca to cause Sarcoplasmic Reticulum to release calcium, increasing intracellular calcium o Cardiac NerveNE Beta cells Gs Turn ATP into CAMP PKA Open CA channels & PKA Increased intracellular Ca Contractio
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