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University of Toronto Scarborough
Biological Sciences
Stephen Reid

Lecture 16 Study Notes Hydrostatic pressure P = Pcapillaries Pisf o ISF = interstitial fluid o Pcap = hydrostatic pressure in capillaries Hydrostatic pressure in capillaries drives fluid out of the capillary (i.e. filtration) and is highest on arterial side, lower on the venous side Causes fluid movement down pressure gradient o Pisf = hydrostatic pressure in the interstitial fluid Oncotic pressure = cap isf o Oncotic Pressure (opposes hydrostatic pressure) is exerted by proteins and drives fluid into capillaries cap = oncotic pressure in the capillaries This pressure is constant throughout the capillary beds Lots of protein in plasma flowing in capillary bed hence oncotic pressure isf = oncotic pressure in the interstitial fluid This pressure is generally 0 in the isf because the has virtually no proteins Net Filtration Pressure = P - o Or NFP = Hydrostatic Pressure (fluid out c) Osmotic Pressure (fluid in c) o If NFP is positive, theniltration of fluid occurs (flowing out of capillaries) o But if NFP is negative, thenabsorption occurs (flowing into capillaries) o Note: On the arterial side of capillary bed, NFP is positive, so fluid is drawn out of capillaries (filtration outward)
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