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Study Guide for Tuberculosis


Department
Health Studies
Course Code
HLTB21H3
Professor
Caroline Barakat

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Disease Origin Transmission Clinical
Manifestations
SymptomTreatment
Tuberculosis
“the white
plague
-Mid 19th
century TB
was
romanticized
-Opera
productions La
Traviata (1853),
La Boheme
(1895)
-Classical
movie Camille
(1936) based
on Alexandre
Dumas novel
The Woman of
the Camellias
1993 , “global
emergency”
2007- WHO ,
epidemic
leveled off.
TB contributed
to culture and
art
- persons with
tb were
considered
beautiful (thin,
long neck ,
hands , shining
eyes, pale skin
and red
cheeks)
Themes of
artistic genius
and eroiticism
wer e
prominent.
-present since antiquity
-found in early mummies
(2400 BC)
-“phtisisor
consumption”- Homer
800 BC
-TB was documented in
Egypt , India , and china
as early as 5000
-TB epidemics likely from
changes in the host
population and the
environment
-In England, practice of
‘Kings Evil or the Royal
Touching’ : but TB Can
become dormant ; they
took credit from this
type of healing.
-1882 Dr. Robert Koch
discovered
Mycobacterium
tuberculosis
-Developed tuberculin’
test
-death rates were higher
among the African
Americans, and it did
NOT affect all segments
of the U.S population.
Caused by tubercle
bacillus germ
Mycobacterium
tuberculosis, an
acid-fast bacillus
-A person may
contract pulmonary
tuberculosis from
inhaling droplets
from a cough or
sneeze by an
infected person.
Forms a Granuloma
in lung tissue.
-several ANIMAL
forms
-Tb can remain
viable throughouse
the hosts lifetime.
- Infection can
remain dormant until
resistance fails.
- Indefinit variable
for incubation period
, TB in lungs are
infectious (ACTIVE)
-enviromental
factors : low protein ,
overcrowding ,
-people with weak
immune systems
,OR hiv/aids have
more chances of
getting TB.
3 main types of the
human bacillus
-Type 1
found in
India; least
virulent
-Type A
Africa,
China,
Japan,
Europe, N
America
-Type B
Exclusively
in Europe
and North
America
a)Bovine TB (come
from cows , and if
milk is not
pasturisized
b) MIliary TB
: small TB in every
organ.
c)Potts Disease
TB in spine (Cannot
be spread to other
people that easily)
Its the fusion of the
vertebrae and
deformation of spine
may lead to
hunchback (Sir
percevial Pott 1779)
Lupus vulgaris
( affects the skin and
the kidneys) causing
painful tuberculosis
skin lesions
Scrofula : Tb
affecting the lymph
nodes in the neck
which causes
swelling.
-nostagalia
-depression
-sexual
indulgence
-Coughing
(persistent
coughing for
three weeks ,
mucus,flem )
- sneezing ,
-spitting
blood ,
- feel sick or
weak ,
-ploose
appetitie
(weight
loss) ,
extreme
thinness ,
fever and
night sweats
(when it
progress)
CHEST PAIN
.
ACTIVE
FORM : they
hide in the
macrophages
-Tuberculin T
- Tb can be
cured by taki
combo of dru
for 6-12 mon
People expo
to active TB
recive preven
therapy for 6
months
Drug Resist
TB :
-Strains that
resistant to a
single drug h
been
documented
every countr
-MDR-TB :
Particulary
dangerous fo
of TB
(Azion Acid ,
Rifapmin)
dr. SELMEN
WAKSMAN
Drug Therap
Discovery of
antibiotics
Nobel Prize
Physiology
Medicine: 19
BCG : Baci
CAlmente-
Guerin : trie
reduce new
infections of
Not in use in
Ontario
Strain of the
bacilli (thats
www.notesolution.com
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