Etiology, Clinical Manifestations, Treatments Exam Review

25 views12 pages
user avatar
Published on 6 Jul 2011
School
UTSC
Department
Health Studies
Course
HLTB21H3
Plagues and Diseases
Etiology, Clinical Manifestations and Treatment
-------------------------------------------------------------
Plagues of Antiquity
- Bubonic Plague [1346 - 1542]
- 2 to 5 days till symptoms
- Lymph node infection with buboes
- Fever feelings + Seizures
- Pneumonic Plague:
- Severe cough, frothy, bloody sputum
- Difficulty Breathing
- Septicemic Plague:
- Abdominal pain
- Anything to deal with circulation processes
- Organ failure, nasea, diarrhea, blood clot
- Black Death
- All 3 plagues
- 30-75% infection mortality rate of bubonic, 90-95% with pneumonic [two most
common]
- First struck ports and then trade routes
www.notesolution.com
Unlock document

This preview shows pages 1-3 of the document.
Unlock all 12 pages and 3 million more documents.

Already have an account? Log in
- Sylvatic Cycle:
- Infection between domestic rodents <-> infective fleas <-> wild rodents -> Humans
- Pneumonic can be airborne
-------------------------------------------------------------
- Leprosy
- Agent: Mycobacterium Leprae
- Chronic Disease / Slow multiplying bacillus, Double time: 12-14 days
- Incubation: 3-5 years
- Thought to be transmitted vida droplets from nose
- Not highly infectious and maybe genetically related with susceptibility
- Mainly affects skin, nerves and mucous membranes
- Clinical Manifestations
- Indeterminate [IL]
- Skin lesions [small, no nerve dmg]
- Loss of sense is rare, majority will develop, those with strong immunity
recovers or turns latent
- Tuberculoid [TT] - 1-2 yrs after exposure
- Deep lesions [nerve dmg / imparement, affected nerves thicken]
[Nerve dmg = less feeling]
- Untreated patients rarely form leprotamous after many years [LL]
- Borderline Tuberculoid [BT]
- Deep lesions but smaller and more [same nerve damage effects + thickening]
www.notesolution.com
Unlock document

This preview shows pages 1-3 of the document.
Unlock all 12 pages and 3 million more documents.

Already have an account? Log in
- May stay or revert
- Borderline Lepromatous [BL]
- Many lesions, papules, plaques and nodules [same nerve damage effects]
- Looks like inverted saucers
- Lepromatous [LL]
- Most severe, never reverts
- Numerous lesions of all kinds
- Skin thickens, losing brows / lashes, photophobia and enlarged nodes +
deformed extremities, hoarse voice
- Treatment:
- Based on symptoms
- Chaulmoogra Nut, Promin, Dapsone, MDT
-------------------------------------------------------------
- Tuberculosis
- Agent: Tubercle Bacillus
- Type: Mycobacterium Tuberculosis, an acid fast bacillus requiring specific ways of
identifying [Affects the spine]
- Type I: Found in india, weakest
- Type A: Africa, China, Japan Europe, NA
- Type B: NA, Eu
- Only bovine types infect humans [suggested through ingestion], leading to
pulmonary TB
www.notesolution.com
Unlock document

This preview shows pages 1-3 of the document.
Unlock all 12 pages and 3 million more documents.

Already have an account? Log in

Document Summary

30-75% infection mortality rate of bubonic, 90-95% with pneumonic [two most common] First struck ports and then trade routes www. notesolution. com. Infection between domestic rodents <-> infective fleas <-> wild rodents -> humans. Chronic disease / slow multiplying bacillus, double time: 12-14 days. Thought to be transmitted vida droplets from nose. Not highly infectious and maybe genetically related with susceptibility. Mainly affects skin, nerves and mucous membranes. Loss of sense is rare, majority will develop, those with strong immunity recovers or turns latent. Tuberculoid [tt] - 1-2 yrs after exposure. Deep lesions [nerve dmg / imparement, affected nerves thicken] Untreated patients rarely form leprotamous after many years [ll] Deep lesions but smaller and more [same nerve damage effects + thickening] www. notesolution. com. Many lesions, papules, plaques and nodules [same nerve damage effects] Skin thickens, losing brows / lashes, photophobia and enlarged nodes + deformed extremities, hoarse voice. Type: mycobacterium tuberculosis, an acid fast bacillus requiring specific ways of identifying [affects the spine]