HLTB21H3 Study Guide - Anopheles, Roman Campagna, Plasmodium Vivax

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Fever plague killed over half of the people who ever lived on the planet. Someone dies every 10 seconds mostly children under 5 in africa. 300 million 500 million cases only 10% outside of africa: 2-3 million deaths. Recorded in ebers papyrus (1570 bc: described: enlarged spleens, periodic fevers, headache, chills, and fevers. Most likely came from africa to europe by either nile valley or close contact between. Hippocrates: 2 types of malaria: recurrent fevers every third day (benign tertian, fevers on every fourth day (quartan) Believed to be from vapors emanating from the marshes (roman campagna) Reached spain and russia by 12th century. Brought to new world by european explorers, conquistadors, colonists and african. Laveran examined blood from soldier suffering from malaria and found transparent globules containing malaria pigment in red blood cells, and sometimes mobile filaments coming from clear spherical bodies(exflagellation) Ross, manson and koch discovered mosquito as vector.

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