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Plagues without germs

3 Pages
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Department
Health Studies
Course Code
HLTB21H3
Professor
Caroline Barakat

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Plagues without germs
The Red Plague first described in Spain 1735 as Mal de la rosa
First appeared as a skin rash that covered the hands and feet and sketched an ugly
butterfly pattern across the neck
Early stages reddening of the skin might resemble a sunburn or inflammation due
to contact with poison oak. The skin crusted and peeled away, showing the smooth
and shiny skin below, tongue became reddened, burning sensation in the mouth ,
and diarrhea.
Pellagra pelle skin. Agra rough
oassociated with people who had a diet of corn
oI. Salas concluded that cause was spoiled corn infested with parasite verdet
Joseph Goldberger experiment: every child under 12 years of age got 14 ounces
of milk a day, and those under 6 years of age got 20 ounces. Eggs and fresh meet
served 4 days a week. Pellagra faded
oConducted another experiment which stated that the lower the income, the
greater the incidence of pellagra
odiscovered that rats and dogs show pellagra like symptoms black tongue
and inflammation of the skin (dermatitis)
oBasic diet 123 consisted of corn meal, cowpeas, casein, sucrose, cottonseed
oil, cod liver oil, sodium chloride, and sodium carbonate
oSprinkling dried brewer`s yeast on basic diet 123 prevented black tongue and
death in dogs
oGreat depression eliminated pellagra
Prevention adding fresh meat, milk, eggs, and vegetables to the diet.
oPellagra preventive factor (P.P)
Deficiency of niacin needed for normal oxidative metabolism of sugars
red plague led to the discovery of antimetabolites drugs designed to inhibit
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Description
Plagues without germs The Red Plague – first described in Spain 1735 as Mal de la rosa First appeared as a skin rash that covered the hands and feet and sketched an ugly butterfly pattern across the neck Early stages – reddening of the skin might resemble a sunburn or inflammation due to contact with poison oak. The skin crusted and peeled away, showing the smooth and shiny skin below, tongue became reddened, burning sensation in the mouth , and diarrhea. Pellagra – pelle – skin. Agra – rough o associated with people who had a diet of corn o I. Salas – concluded that cause was spoiled corn infested with parasite verdet Joseph Goldberger – experiment: every child under 12 years of age got 14 ounces of milk a day, and those under 6 years of age got 20 ounces. Eggs and fresh meet served 4 days a week. Pellagra faded o Conducted another experiment which stated that the lower the income, the greater the incidence of pellagra o discovered that rats and dogs show pellagra like symptoms – black tongue and inflammation of the skin (dermatitis) o Basic diet 123 – consisted of corn meal, cowpeas, casein, sucrose, cottonseed oil, cod liver oil, sodium chloride, and sodium carbonate o Sprinkling dried brewer‘s yeast on basic diet 123 prevented black tongue and death in dogs o Great depression eliminated pellagra Prevention – adding fresh meat, milk, eggs, and vegetables to the diet. o Pellagra preventive factor (P.P) Deficiency of niacin – needed for normal oxidative metabolism of sugars red plague led to the discovery of antimetabolites – drugs designed to inhibit www.notesolution.com bacterial growth by interfering with their coenzymes or enzymes White Rice Plague – neurological disorder characterized by paralysis of the hands and feet native name beriberi, which meant ‘‘ ì cannot‘‘ Symptoms – loss of strength, loss of appetite, swelling of the ankles and thighs with great pain in the leg joints, loss of the ability to speak, emaciation, and death from
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