Antiquity of human malaria is reflected by evidence in the ebers papyrus in clay tablets from the library of king ashurbanipal and in the chinese medical text, the nei chang. Describes typically large spleen, periodic fevers, headache, chills and fever. Malaria probably came to europe from africa by the nile valley or through direct contact between. Diseasae was so prevalent in marshland of the roman campagna that the condition was called roman. Fever recurred during summer season due to vapors emanating from the marshes bad air . 12th century it was in spain and russia. Malaria brought to the new world by european explorers, conquistadors, colonists, and african slaves. Found within red blood cells transparent globules containing black-brown malaria pigment and, on occasion, mobile filaments emerging from clear spherical bodies (exflagellation) Also found some patients had blood cells shaped like crescents. Discovered an animal parasite with different developmental stages.