HLTB21H3 Midterm: Test 3 notes

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14 Apr 2011
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Described1122 bc in china and is mentioned in ancient texts of india -100ad plague of antonine. Europe - frequent epidemic during the middle ages. 16th century became a serious disease in england and europe. Plague of antonine -new world in the 16th century - fall of the empires of the aztecs and the incas -contributed to the settlement of n america by the french & English (1617) -biological warfare: french-indian war (1754 1767) - deliberate use of smallpox -slave trade. Virus : genus - orthopoxvirus, family poxviridae -common name - variola virus. 30% - 50% in unvaccinated -hemorrhagic smallpox or black pox -malignant and hemorrhagic forms of variola major develop in approximately 5 to 10% of infected people -almost always fatal; mortality rate of 95% Continuously transmission required -only short-term carriers -animal reservoirs do not exist -direct contact - inhalation of aerosols or contaminated fomites.

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