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Exam review notes part 5

2 Pages
Winter 2011

Health Studies
Course Code
Caroline Barakat
Study Guide

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Disease Plagues
without germsPallagara (Red disease)Beriberi (White rice plague) Scurvy (explorers disease)Rickets
Historical ContextSpain 1735
Pella’ ‘agra Italian for
skin rough
1909: Epidemic in US (26
1912: high fatality (SA-40%)
20th century: 3M cases in
US and 1000 deaths
Old belief: INFECTIOUS
disease of the poor
1939: evidence established
that it was die to niacin-
deficiency (Vitamin B3)
1616: neurological disorder
characterized by paralysis
of hands and feet
Early 1900s: Eijkman did
chicken study and
established: disease is not
1926: deficiency in
thiamine (Vitamin B1)
15th century: early records
16th century: men in sea
voyages were noted to have
gums that grew over their
teeth could not eat 
18th century: James lind
did the first controlled
clinical trial: disease was
related to nutrition and
lemon juice intake
19th century: Outbreaks in
Ireland, California, and NY
Old disease
1650: epidemic in England
Late 19th century: the
disease was restricted to
industrial cities: Scotland,
England, N-Europe
Epidemiology1730-1930: 1 million deaths
1950: eradicated
1917-1921: Goldberger: did
an epidemiological study:
cause = diet
Bread enhancement
and mandatory
enrichment laws
since 1938 led to a
major decline in
Blacks are more susceptible
(Vitamin B3)
Needed for nomal
oxidative metabolism
of sugars
thiamine (Vitamin B1)
Necessary for
normal cell
metabolism of sugar
and alcohol
Vitamin C deficiency
Deficiency in vC
shuts down the
synthesis of collagen
deficiency of solar
ultraviolet radiation
It act as a sterol to
produce calciferol
(vitamin D3)
Calciferol becomes
calcidol, then
calcitrol a
hormone that
promotes the
absorption of calcium

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Disease Plagues Pallagara (Red disease) Beriberi (White rice plague) Scurvy (explorers disease) Rickets without germs th Historical Context Spain 1735 1616: neurological disorder 15 century: early records Old disease Pella agra Italian for characterized by paralysis 16 century: men in sea 1650: epidemic in England skin rough of hands and feet Late 19 century: the voyages were noted to have 1909: Epidemic in US (26 Early 1900s: Eijkman did gums that grew over their disease was restricted to States) chicken study and teeth could not eat industrial cities: Scotland, 1912: high fatality (SA-40%) established: disease is not death England, N-Europe th 20 century: 3M cases in germ-related 18 century: James lind US and 1000 deaths 1926: deficiency in did the first controlled NOT POOR DIET, IT IS thiamine (Vitamin B1) clinical trial: disease was DUE TO AIR POLLUTION Old belief: INFECTIOUS related to nutrition and disease of the poor lemon juice intake 19 century: Outbreaks in 1939: evidence established Ireland, California, and NY that it was die to niacin- deficiency (Vitamin B3) Epidemiology 1730-1930: 1 million deaths
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