Why was it hard to Dating back to the 7th century, people were
distinguish measles? confused with the similar symptoms from
other rash diseases like smallpox.
Who attributed the Rhazes (900AD) clinically separated
earliest description of smallpox and measles. Noticed that the pupil
measles? of the eye gets smaller when exposed to
light. He also believed that both proceeded
from same cause.
What was the prevailing red rash represented the mothers menstrual
theory about measles in blood that accumulated in the child during
the past? its time in the womb. Measles was a way for
children to rid themselves of the so called
poisons so the disease was welcomed.
What are other names for rubeola, hard measles, red measles, morbilli,
measles? hasbah. The origins of the term measles is
from Latin - misellus or misella meaning
In 1670 what did ThomasClearly separate measles from smallpox and
Sydenham first do? recognized complications such a cancrum
oris (leads to the destruction of the mouth)
and encephalitis (swelling of the brain).
By now what theory haveMother bloods theory
In 1757 what did Francis demonstrated the infective nature - he
Home demonstrate? succeeded in transmitting measles using
blood from an infected child to 8 other
What is viral The swelling of the brain and : may develop
encephalitis? during or after infection an its not only
restricted to measles but others like herpes,
What is cancrum oris? Destruction of the tissue of the nose and
What scientist did the Peter Ludwig Panum ( 19th century)
Danish government send
to the Faeroe Islands?
Why did the Danish They sent him to the Faeroe Islands tobe the
government send Peter first to observe the measle epidemic and find
Ludwig Panum? different features of the disease.
Approximatly 7,800 inhabitants and 102 died (1846).
Why was Faeroe Islands Faeroe islands were ideal for
significant? epidemiological study of the measles. The
islands have small isolated communities and
all visitors were noted in a calendar. Panum
was able to trace the start of the epidemic
and establish 4 important facts.
What are the 4 important 1.) Rash appears 12 to 14 days after contact
facts Panum established? with an infected person.
2.) Infectivity is greatest 3-4 days before the
3) Contagious nature of disease - respiratory
rout of transmission.
4.) Life-long immunity ( those contracted
before did not get it again).
What did Hektoen In 1910 he demonstrates that the disease is