Exam Study Guide - Leprosy, Tuberculosis, Syphilis

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Health Studies
Caroline Barakat

Leprosy (Hansens disease) History 1550BC Egyptian Papyrus document Approx. 600BC Indian writings 320BC Records in Ancient Greece, after army of Alexander the Great returned from India 62BC - Rome returned with Pompeiis troops from Asia Minor Disease of soul Thought to be hereditary illness, caused by a curse or punishment of God Lepers were stigmatized special clothing, arrival notification, separate hospitals, leprosariumslazarettoleper colonylazar house 936AD England - First leper house th Mid-12 century loss of civic status removal from public office; 13 century - 19,000 leprosaria in use Mass of Separation Decline around 1350 AD Spread to North America Dr. Armauer Hansen of Norway 1873 Discovers the leprosy germ under a microscope Mycobacterium leprae (M. leprae ) Etiology Slow multiplying bacillus - average doubling time of 12 14 days Incubation period of 3 5 yrs Thought to be transmitted via droplets, from the nose during close and frequent contact Not highly infectious may be related to genetic susceptibility Mainly affects the skin, nerves, and mucous membranes Risk All races; common in warm, wet areas in the tropics and subtropics; Most susceptible between the ages of 10 and 14 years old, 35-44 years old Rarely seen in infants; Genetic susceptibility Diagnosis and Treatment Based on clinical symptoms; laboratory studies Chaulmoogra nut promin (1941) Dapsone (1950s) WHO recommends multidrug therapy (MDT) dapsone, rifampicin, clofazimine www.notesolution.com
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