NROC61H3 Study Guide - Sickness Behavior, Hyperalgesia, Prostaglandin E2

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1. fat mass set point: what happens if you go over or under the set point, over. 1. leptin / insulin levels increase: cart / pomc activated a. increase in a-msh release, npy / agrp inhibited, decrease in npy / agrp release. 4. result: a. increased metabolism: decrease in food intake, under. 1. leptin / insulin levels decrease: npy / agrp activated a. increase in npy / agrp release, cart / pomc inhibited, decrease in a-msh release. 4. result: decreased metabolism b. increased food intake regulatory mechanisms for feeding. 3. internal factors: orexigenic signal, ghrelin, hunger signal increases appetite. Cck: mediates pre-absorptive satiating effect of fats, anticipatory aspect, may be critical in regulating the intake of fat, a receptor binding is important, direct association between cck and fat consumption. 3. outside of the hypothalamus: downstream brainstem a. b. fundamental aspects of consumption not affected by decerebration.

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