BIO130H1 Study Guide - Midterm Guide: Circular Rna, Membrane Transport Protein, Eukaryotic Transcription
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BIO130H1 Full Course Notes
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Dna or rna: bacteria have a cell wall, cytoplasm, dna in a chromosome, maybe plasmids, and flagella. Information in protein can go back and affect the dna through rna/transcriptome and what actually gets transcribed. Nucleoside monophosphate: sugar + base + 1p (amp) Dna"s (cid:271)uildi(cid:374)g (cid:271)lo(cid:272)ks are (cid:374)u(cid:272)leotides: nu(cid:272)leotide 5" e(cid:374)d = phosphate, sugar phosphate group is on the outside = negative charge. Dna functions: storage of genetic information, replication and inheritance, expression of the genetic message (directs order of amino acids) Nucleic acid chains: dna is synthesized from deoxyribonucleoside triphosphates, aka dntps, rna is synthesized from ribonucleoside triphosphates aka ntps, nucleotides are linked by phosphodiester bonds. Base pairing: holds the dna double helix together, a-t, the 2 h-bonds are straight, g-c, 3 h-bonds (complementary h-bonding) Ensures that strands are complementary, important for transcription. Tra(cid:374)ds are a(cid:374)tiparallel= 5"-3" a(cid:374)d part(cid:374)er is 3"-5". Most protein made in major group bc minor too narrow. G-c rich dna is more stable at high temperatures.
