BIO130H1 Study Guide - Midterm Guide: Cleavage And Polyadenylation Specificity Factor, Nucleotide Excision Repair, Protein Structure

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University of Toronto
(St. George)
BIO130H1
Molecular and Cell Biology
Winter 2018
Term Test 1
Professor: Kenneth Yip
Exam Guide
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Table of content
- Introduction to Cell and Molecular Biology
- Molecular Interactions and Introduction to Proteins
- Protein Structure and Synthesis
- Genomes and Chromosomes
- Nucleosomes and DNA Synthesis
- Bacterial DNA Replication
- DNA Repair and Errors in DNA Replication
- DNA Repair and RNA Transcription
- RNA Transcription in Eukaryotes
- mRNA Processing and Translation in Eukaryotes
- Translation in Prokaryotes and Eukaryotes
- Phospholipid Bilayers
- Membrane Proteins and the Permeability of the Lipid Bilayer
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Introduction to Cell and Molecular Biology
BIO130 Overview
Overall objectives of this course:
o Provide knowledge and preparation for upper year courses
o Examine some highlights of the “biological revolution” underway
o Discover some connections between basic molecular and cell biology research
and its application in our lives
Overall topic:
o Life inside a cell
Section 1 Lectures
Cellular and Genomic Diversity
o Prokaryotes and Eukaryotes
Differences and similarities
General organization
Origins
o Model Organisms
Examples and how they are used
The Molecules of Life
o General concepts about:
DNA
Nuclear and organellar genomes
Chromosomes and chromatin
DNA replication and repair
Genomics
RNA
General characterization of transcription
RNA processing
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