BIO130H1 Study Guide - Final Guide: Keratin, Peroxisome, Hepatocyte

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University of Toronto
St. George
BIO130H1
Molecular and Cell Biology
Winter 2018
Final Exam
Professor: Kenneth Yip
Exam Guide
Part 2 of 3
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CONTENTS
Exam Guide Covers the Following Topics:
Section 2: Cellular Form and Function
Part 2 of 3
Intercellular Compartments and Protein Sorting
Protein Sorting Mechanisms
The Cytoskeleton
Microtubules, Actin Filaments, and Intermediate Filaments
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Intracellular Compartments and Protein Sorting
Intracellular Compartments
Hepatocytes (liver cells) function in detoxification
Table: percentage volumes occupied by organelles in a standard cell (note that volumes
will be different in different cells)
Cytosol occupies half the cell volume
oIt is used in protein synthesis and degradation
oIt is also used in intermediary metabolism (degradation and synthesis of small
molecules)
Organelles
Organelle a subcellular compartment or large macromolecular complex, often
membrane-enclosed, that has a distinct structure, composition and function
oExamples of membrane enclosed organelles: nucleus, endoplasmic reticulum,
Golgi apparatus
oExamples of organelles that are not membrane-bound: nucleolus, centrosomes
oNote: ribosomes are too small to be classified as organelles
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