BIO130H1 Study Guide - Quiz Guide: Helicase, Alpha Helix, C-Peptide

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16 Oct 2018
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TEXTBOOK QUIZ #1
1. A group of molecular cell biologists are attempting to synthesize a compound to minis the
effects of a well-known hormone that affects digestion. They would like your advice about how
to go about this. Using your knowledge and reasoning, which of the following compounds is
most likely to mimics the effects of the hormone
A compound with the same number of carbon atoms as the hormone
B compound with the same 3D shape as the hormone
C compound with the same molecular mass as the hormone
D compound with the same number of hydrogen and nitrogen as the hormone
2. Why are alpha helices and beta sheets common folding patterns in polypeptides??
A Amino acid side chains are not involved in forming the hydrogen bonds, allowing many
different sequences to adopt there folding patterns
B molecular chaperones tend to fold polypeptides in these folding patterns
C there are no correct answers
D the unique amino acid sequences that generate these folding patterns are common in
polypeptides
3. Extracellular proteins are directly exposed to extracellular conditions. To help maintain their
specific 3D shape, polypeptide chains are often and I kid there
A ester bond
B disulfide bonds
C peptide bonds
D hydrogen bonds
4. Which of the following statements describes the eukaryotic chromosome
A nucleosome is its most basic functional subunit
B compose DNA alone
C number of genes on each chromosome caries in different cell types of organism
D consists of single linear molecule of double stranded DNA plus protein
5. If a cell were unable to produces histone proteins. Which of the following would be a likely
effect?
A amplification of other genes would compensate, most likely
B spindle fibers would not form during prophase
C cells’ DNA couldn’t be packed into its nucleus
D Transpsosons would be transcribed to compensate for decreases proteins in the cell
TEXTBOOK QUIZ #2
1. In PCR, we use heat to separate the DNA strands instead of a helicase
A True
B False
2. Which of the following is true for most genes?
A all answers are correct
B A gene is a segment of DNA that contains the instructions for making a particular RNA
C A gene is a segment of DNA that contains the instructions for making a particular protein
D A gene is a region of DNA that controls a discrete hereditary characteristics of an organism
3. Which of the following statements is correct?
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A DNA polymerase catalyzes the addition of nucleotides with no “proof-reading”
B DNA replication does not involve RNA- RNA is involved in transcription and translation
C single stranded DNA-binding proteins stabilize the unwound, single stranded conformation
of DNA
D Exonucleases cleave nucleotides one at a time from the ends of polynucleotides to cause DNA
replication errors
4. In order for DNA replication by DNA polymerase to occur, a number of accessory proteins are
required. Which of the following is the most probable sequence in which proteins would need to
act for DNA replication to occur: 1. DNA ligase 2. Single stranded binding protein 3. DNA primase
4. DNA helicase
A 2,4,3,1
B 1,2,3,4
C 4,3,2,1
D 4,2,3,1
E 3,1,2,4
5. DNA can be replicated only in the 3’ to 5’ direction
A True
B False
TEXTBOOK QUIZ #3
1. How does UV radiation in sunlight typically damage DNA?
A It removes bases from nucleotides in DNA
B Breaks hydrogen bonds between the two strands of DNA
C Promotes covalent linkage between 2 adjacent pyrimidine bases
D There is no correct answer
2. When does DNA polymerase perform its proofreading function on mispaired nucleotides?
A There is no correct answer
B After adding a stretch of about 100 more nucleotides
C Before adding the next nucleotide in the chain
D After finishing the DNA strand
3. Which of the following statements concerning DNA repair is correct?
A DNA polymerase is used in both base excision repair and nucleotide excision repair
B DNA glycosylases are used in base excision repair
C All statements are true
D DNA repair mechanisms act on both transcribed and non-transcribed DNA
E Nucleotide excision repair helps repaid “bulky lesions”
4. An RNA chain elongates in the 5’ to 3’ direction
A True
B False
5. The enzyme telomerase solves the problem of replication at the ends of linear chromosomes by
which method?
A Adding numerous AT pairs which allows the telomeres to easily unwind
B Causing linear ends of the newly replicated DNA to circularize
C Adding numerous GC pairs which resist hydrolysis and maintain chromosome integrity
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