BIO230H1 Final: Complete Exam Review

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BIO230H1 Full Course Notes
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BIO230H1 Full Course Notes
Verified Note
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This change could lead to disease and so must be controlled. How cells organize tissues spatially: membrane trafficking, cytoskeletal networks, cell adhesion. Function: engage environment, cell-to-cell communication (example: nerves, acquiring resources (example: gut lining epithelium) Mechanism: dynamic change and control of plasma membrane. Compartments for trafficking: vesicles, er, golgi, endosomes, lysozomes. Pathway principles: polarized trafficking routes: one end is different from another, sorting stations, retrieval mechanism and balance of routes: matching endocytosis with exocytosis. Constitutive secretory pathway: continuous exocytosis (vesicle docks and fuses with plasma membrane) continuous pumping. Regulated secretory pathway: cargo is stored in vesicles and only secreted by signal activation. Mechanisms of both pathways are similar: cargo is concentrated into a vesicle barrier still present, vesicle docks and fuses (removes barrier) Example #1: mast cell (immune cell) releases stored histamine (increases attack abilities) after induction (signal) by a soluble extracellular stimulant in response to invasion) Function: to counter-balance exocytosis and perform specific functions.