BCH210H1 Study Guide - Final Guide: Ferrous, Heme, Deoxygenation
49
BCH210H1 Full Course Notes
Verified Note
49 documents
Document Summary
If you are a large animal you need the circulatory system to distribute oxygen evenly. Here we are talking about oxygenation (o2 coming in) want to promote it (avoid oxidation -would kill hemoglobin) Hemoglobin has a quaternary structure (alpha 1 , alpha 2, beta 1, beta 2) ****(4 subunits of monomers: two types of subunits alpha and beta and two of each. These subunits are not covalently linked- largely ionic and non-covalent bonds. Organic molecule not an amino acid. It"s attached to the amino acid hemoglobin. It"s not ferric ion(otherwise it would burn upone binding of oxygen) it"s ferrous (to allow oxygen to bind ) Know that there are number of pyrolle rings fused together to give highly unsaturated structure with the iron sitting in the middle. Don"t worry about drawing the entire structure. Similar to one of the subunits of hemoglobin. Oxygen on the top is stabilized by h- bonding. Hemogoblin carrys o and drops it where needed.
