BCH210H1 Study Guide - Phosphatidic Acid, Cw Complex, Oleic Acid

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Biochemistry I
MEMBRANE PROTEIN, TRANSPORT,
SIGNALLING AND PREDICTION OF PROTEIN
STRUCTURE
BCH210H1F
1BCH210 Study Group I
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Overview of Session
Reithmeier:
I. Lipid Structure and Functions
II. Functions and Features of Biological
Membranes
III.Membrane Proteins: Structure, Properties
and Function
Deber:
IV. Prediction of Protein Structure
BCH210 Study Group I 2
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Document Summary

Therefore, the phosphate group acts as a bridge between the backbone and the alcohol (through phosphodiester linkages). Common fatty acids (a) (b: space-filling models of (a) palmitate (c16, saturated) and (b) oleate (c18, unsaturated). The cis- double bond in oleate produces a kink in the hydrocarbon chain. Naming fatty acids: shorthand designation c x:y. Structure of bilayers stearate (saturated) oleate (unsaturated: van der waals interactions hold these fatty acid chains together, the longer the chain the more. Van der waals interactions and the more stable the structure. The kink due to the cis-double bond disrupts the van der waals interactions, and there is no good packing. Note: important for signaling as it has a (-) charge overall as a phospholipid. Cholesterol: origins: this sterol is present in. Most prokaryotes: the oxygen atom in its 3- Cholesterol: the facts: cholesterol is good for you (of course too much is bad!, looks very different, fused rings.

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