Study notes for midterm

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Department
Biochemistry
Course
BCH210H1
Professor
Dave Tulumello
Semester
Fall

Description
Lecture 3September 16 2011 DavidtulumelloutorontocaLevels of protein structure Alphahelix CO from residue number 1Hydrogen bonded to the NH amino acid number fiveBonding of i to i4 or from 1 to 5Making spiral360 degrees so positioned under carbonyl of residue 1so favourable geometric situation so spiral Helix is always touch with environment with side chainsBetapleated sheet Zigzag chains Chains bonded to each other through alternating hydrogen bondsINTERMolecular Helix is single strand single compensated with hydrogen bonds down its peripheryOne strand bonded to second strandso at least two strandsINTERmolecular hydrogen bonded structureexample of Within same protein or between subunits of different proteins Anti Parallelo Refers to direction of peptide bondC O NH o R groups must find position where they pack well not interfere with each other
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