Study Guides for CSB428H1 at University of Toronto St. George (UTSG)

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UTSGCSB428H1U.TepassFall

2008 EXAM ANSWER

OC3713 Page
24 Dec 2010
35
Exocyst components (sec5, 6, 10, 15) act together to tether re with pm to coordinate plasma targeting of. Specifically, arm binds sec10 and rab11 binds
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UTSGCSB428H1U.TepassFall

2009 EXAM ANSWER

OC3717 Page
24 Dec 2010
20
Drosophila sec5, sec6 and sec15 tethers de-cad vesicles originating from the re to lateral membrane for exocytosis. Sec10 at pm and arm act as a landma
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UTSGCSB428H1U.TepassFall

Article #8 Summary

OC3712 Page
24 Dec 2010
18
Astral mt, kinesin, dlg induce cortical polarization of pins/gi in neuroblasts. The cortical domain generates spindle asymmetry, daughter cell size as
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UTSGCSB428H1U.TepassFall

Article #7 Summary

OC3712 Page
24 Dec 2010
27
 cdc42 colocalize with par-6-apkc at the apical cortex in a baz dependent manner. Loss of cdc42 or cdc42-dn disrupts polarity and has cytoplasmic par-
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UTSGCSB428H1U.TepassFall

CSB428H1 Study Guide - Immunoprecipitation, Epistasis, Cantharidin

OC3712 Page
24 Dec 2010
31
 baz phosphorylation site bind pdz of sdt to recruit sdt to pm. Phosphorylation of baz causes it to dissociate from sdt. Non-phosphorylatable baz bloc
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UTSGCSB428H1U.TepassFall

Article #5 Summary

OC3713 Page
24 Dec 2010
23
Csb428h1f article #5: morais-de-sa et al. apkc phosphorylation of bazooka.  baz localizes below par-6/apkc and excluded from apical domain by apkc pho
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UTSGCSB428H1U.TepassFall

Article #4 Summary

OC3713 Page
24 Dec 2010
41
Pten localizes to apical pm to increase pi45p2 by decreasing levels of pi345p3. Ectopic pi45p2 at basolateral surface cause apical proteins to relocate
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UTSGCSB428H1U.TepassFall

Article #3 Summary

OC3713 Page
24 Dec 2010
27
Par-1 phosphorylates baz on two conserved serines, which is then bound by 14-3-3. This inhibits the baz/par-6/apkc complex by preventing baz oligomeriz
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UTSGCSB428H1U.TepassFall

Article #2 Summary

OC3713 Page
24 Dec 2010
31
 os discs are renewed whereby rhodopsin-laden vesicles in the os axonemal cytoplasm fuse with nascent discs abundant in pi3p and fyve domain protein s
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UTSGCSB428H1U.TepassFall

Article #1 Summary

OC3713 Page
24 Dec 2010
29
Loss of exocyst sec5, sec6 and sec15 in fly epithelia results in de-cad/arm accumulating in enlarged rab11 recycling endosome (re).  rab11 interact wi
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