CSB428H1 : Article #8 Summary

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crimsonwombat705

24 Dec 2010

School

UTSG

Department

Cell and Systems Biology

Course

CSB428H1

Professor

U.Tepass

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Document Summary

Astral mt, kinesin, dlg induce cortical polarization of pins/gi in neuroblasts. The cortical domain generates spindle asymmetry, daughter cell size asymmetry and sibling fates. kinesin localizes to (+) ends, and dlg/kinesin, dlg/pins co-immunoprecipitate, suggesting polarity is induced by dlg/kinesin interactions. mt/kinesin/dlg pathway acts in parallel to inscuteable/par pathway, but inscuteable pathway is at prophase coordinating with cns and mt pathway is at metaphase coordinating mitotic spindle axis. neuroblast cortical polarity involves baz/apkc/par-6 and insc, partner of insc (pins), gi to the apical cortex during interphase. at metaphase nmy-2, dlg, scrib and lgl localize to apical as well. Astral mt induce pins/gi/dlg cortical polarity at metaphase insc mutant lacks apical insc/baz/apkc/par-6, but pins/gi/dlg still formed crescents. The crescents were found all around cortex abnormally and delayed from prophase to metaphase. This suggests formation of pins/gi/dlg crescents at metaphase is independent of insc/par pathway. mt disrupting agent colcemid treatment of insc mutant caused loss of pins/gi/dlg crescents.

Related Questions

31.????? interphase A. cytoplasm divided between the two daughter cells

32.????? chromosomenumber B. final phase of mitosis; daughter nuclei form

33.????? chromatid C. sum total of chromosomes in all cells of a given

type

34.????? cytokinesis D. chromosomes condense and mitotic spindle

begins to form

35.????? metaphase E. chromosomes line up at spindle equator

36.????? alleles F. sister chromatids separate, move to opposite

spindle poles now

37.????? prophase G. none between meiosis I and II

38.????? telophase H. half of a chromosome in prophase

39. ????? anaphase I. different molecular forms of the same gene

Matching

ultramarineporpoise990

Part A:

In prokaryotes and eukaryotes cell reproduction is similar in that it requires some kind of signal to proceed, DNA replication, careful separation of the DNA into two equal portions, and division of the cytoplasm. How is cell reproduction different in prokaryotes and eukaryotes?

Select one:

a. In a eukaryotic organism, the signals for cell division are usually not related to the environment but to the function of the entire organism.

b. Eukaryotic cells constantly divide whenever environmental conditions are adequate and the cells are large enough.

c. The linear chromosomes in prokaryotes are constantly being updated.

d. Prokaryotic cell division requires cytokinesis before mitosis because of their small size.

e. The sexual phase of most prokaryotes (bacteria) is essential to the rapid cell division required for infection.

Part B:

What does the name Cyclin Dependent Kinase stand for?

Select one:

a. A protein important to the cell cycle that is dependent on DNA synthesis.

b. An enzyme that cuts DNA so that chromosomes can segregate.

c. An enzyme that phosphorylates other proteins using ATP only when the protein Cyclin is bound to the enzyme.

d. An enzyme that rolls along microtubules dragging a vesicle.

e. An enzyme that connects chromosomes to the spindle fiber.

Part C:

The Cell Cycle is divided into Mitosis, Cytokinesis, and Interphase. Mitosis can be ordered into the following phases:

Select one:

a. Prophase/Prometaphase/Metaphase/Anaphase/Telophase

b. Anaphase/Prometaphase/Metaphase/Prophase/Telophase

c. Metaphase/Anaphase/Telophase/Prophase/Prometaphase

d. Telophase/Prophase/Prometaphase/Metaphase/Anaphase

e. Anaphase/Telophase/Prophase/Prometaphase/Metaphase

Part D:

The Cell Cycle is divided into Mitosis, Cytokinesis, and Interphase. Interphase can be ordered into the following phases:

Select one:

a. S/G1/G2

b. G2/G1/S

c. G1/S/G2

d. G2/S/G1

e. G1/G2/S

amethystyak657

Question 1 (2 points)

In which phase of cell division is marked by the dissolution of the nuclear membrane, the condensation of chromosomes, and the formation of the mitotic spindle?

Question 1 options:

	prophase
	metaphase
	telophase
	anaphase

Question 2 (2 points)

The physical separation of cells during cell division is called:

Question 2 options:

	Cytokinesis
	Telophase
	Interphase
	Chromosome
	Cell plate

Question 3 (2 points)

Meiosis is necessary for sexual reproduction; the gametes formed during this process before fertilization are _______________.

Question 3 options:

	Haploid
	Diploid
	Zygote
	Homologous
	Tetrads

Question 4 (2 points)

Mitosis is the process by which a ___________ cell separates the chromosomes in its nucleus into two identical sets of nuclei.

Question 4 options:

	eukaryotic
	prokaryotic
	bacterial
	all of these are correct

Question 5 (2 points)

Which of the following statements about crossing over is INCORRECT?

Question 5 options:

	It occurs between homologous chromosomes
	It allows for two parents to produce many different types of offspring
	It contributes to genetic diversity in a population
	It occurs during prophase I of mitosis

CSB428H1 : Article #8 Summary

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