CJH332H1 Study Guide - Final Guide: Laser Capture Microdissection, Cholera Toxin, Atrx
Document Summary
Cjh332 lecture 16 what happens to the brain during aging. Pns has repair mechanisms; cns has little repair mechanism, little growth, little repair after damage. Pns has good functional recovery: which neurons sprout new axons. Proteins related to which neurons do/do not regenerate: many neural changes in young animals, few neural changes in aged animals. Regardless of physical fitness, genetic background, diet, rest, stress management, age increases risk of stroke. +60 years old, risk of stroke increases dramatically. Glo(cid:271)al (cid:271)u(cid:396)de(cid:374) of st(cid:396)oke is highe(cid:396) tha(cid:374) alzhei(cid:373)e(cid:396)(cid:859)s a(cid:374)d othe(cid:396) (cid:374)eu(cid:396)odege(cid:374)e(cid:396)ati(cid:448)e diseases. Global burden of stroke inc(cid:396)easi(cid:374)g faste(cid:396) tha(cid:374) othe(cid:396) (cid:272)o(cid:374)ditio(cid:374)s, i. e. alzhei(cid:373)e(cid:396)(cid:859)s, (cid:272)a(cid:374)(cid:272)e(cid:396), hiv/aid . 70% of strokes are preventable, can control high bp through medication or exercise. Therapeutic window: 3 hours after stroke, can supply blood to prevent neural tissue death. Depends on where blood vessel has been blocked. Paresis motor areas affected, weakness of motor movements. Hemiplegia paralysis of one side of body if one side of brain affected.
