HMB200H1 Study Guide - Final Guide: Nernst Equation, Resting Potential, Saltatory Conduction

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16 Apr 2017
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Upon receiving signal from other neurons, voltage changes passively diffuse integration zone: where large # of voltage-dependent ion channels exist. Voltage accumulates the more channels open, the more channels then open: more depolarized more channels open. All of nothing response doesn"t vary in degree. Refractory periods: na+/k+ pump, repolarizes from undershoot, to resting membrane potential. Passive diffusion of ions allows action potentials to diffuse down the axon: opens adjacent ion channels. Allows saltatory conduction: propagation of action potentials at successive nodes of ranvier. Rate law: intensity is represented by the rate at which the axon fires: higher intensity more frequent firing of ap"s, consistent stimulus same frequency of aps. Plasticity is a fundamental feature of the nervous system: dynamic channel functions, changes in channel function, different types of channel subunits, different types of channels, evolutionary processes. Hyperpolarizing afterpotentials small changes of postsynaptic voltage, alone not strong enough to generate an action potential.

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