IMM250H1 Study Guide - Quiz Guide: Cd14, Tlr9, Shigella Flexneri
Document Summary
Innate denotes a property of some thing or action which is essential and specific to that thing or action, and which is wholly independent of any other object, action or consequence. Also known as inborn : dont need prior exposure, represents the immune system in most multicellular organisms (from plants, sea urchins, flies etc. ) In all multicellular organism: conserved throughout evolution, organisms possess a set number of recognition molecules, cells are immediately active, has no memory. Adaptive immunity: evolved 500 million yrs ago, unique to vertebrates, cells require priming, provides memory of infection, memory - immunized react quicker. Innate and adaptive immunity work together in humans. In normal individuals, infections are cleared by the innate and adaptive immune responses. In the absence of adaptive immunity, infection are first controlled by innate immunity but cannot be cleared. In the absence of innate immunity, infections cannot be controlled.
