IMM250H1- Final Exam Guide - Comprehensive Notes for the exam ( 34 pages long!)

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29 Mar 2018
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Lecture 1 - general overview of immune system. Recognize, attack, destroy foreign entities that can endanger our health. Have to adapt to both types of hosts. Recognition and response to threats: entry of pathogen, recognition, challenge: variation in pathogens, different protein structure, can mutate / evolve quickly, response. Ex: hiv aids: challenge: pathogens give out toxins quickly. After infection recruited to site of infection. First concept of immunity in the context of disease. Peloponnesian war between sparta and athens - 430 bc. Spartas victory was partly because of an illness in the athenian army. Made connection between those that recovered from their illnesses and their resistance to secondary infection. In india in 1000 bc and ancient egypt and china. Killed of european population in 1700s. 1776: smallpox outbreak was an important factor in the american defeat in the battle of quebec. 1700s europe - 400,000 deaths per year from smallpox.

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