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Final

IMM250H1 Study Guide - Final Guide: Ruslan Medzhitov, Antonie Van Leeuwenhoek, Mycobacterium Tuberculosis


Department
Immunology
Course Code
IMM250H1
Professor
Dana Philpott
Study Guide
Final

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IMPORTANT NAMES AND THEIR ACHIEVEMNTS
Thucydides: Connection between those who survived the illness and their later
resistance to it.
Zabediel Boylston and Cotton Mather: Introduced the process of inoculation
Lady Mary Wortely: Saw the trail of variolation and they it became important;
The Royal Experiment
Edward Jenner: inoculated people with cowpox to develop immunity from
smallpox
Antonie van Leeuwenhoek: discovered microbes
Louis Pasteur: disproved spontaneous generation and developed vaccines for
rabies, cholera and anthrax and showing that heat can kill germs
(pasteurization)
Robert Koch: discovered anthrax and tuberculosis (caused by mycobacterium
tuberculosis)
Robin Warren and Barry Marshalls: discovered and proved that H. pylori is the
cause of gastritis and gastric ulcers using Koch postulates
Christiana Neusellin Volhard: identified the drosophila toll in fruit fly, which
was involved in embryo development and adult immunity
Ruslan Medzhitov and Charles Janeway: discovered the mammalian toll called
the TLR4
Ilya Metchnikoff: Cellular approach of immunity; phagocytosis
Paul Ehlrich: Humoral approach towards immunity; antitoxins from cells; side
chain theory
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