Study Guides (390,000)
CA (150,000)
UTSG (10,000)
IMM (70)
Midterm

IMM250H1 Study Guide - Midterm Guide: Gram-Negative Bacteria, Innate Immune System, C3B


Department
Immunology
Course Code
IMM250H1
Professor
Dana Philpott
Study Guide
Midterm

This preview shows pages 1-2. to view the full 7 pages of the document.
UNIVERSITY OF TORONTO
Faculty of Arts and Science
Midterm Exam, Spring 2018
IMM250H1S
Wednesday, February 7, 2018
Duration - 2 hours
No aids allowed. Please use pencil.
After completing this exam,
you may NOT take the exam paper with you.
This test consists of a total of 30 multiple-choice questions, and is
worth 30% of the final course grade
BE SURE TO COMPLETE
YOUR NAME AND STUDENT NUMBER
ON THE SCANTRON SHEET
(NO COURSE CODE)

Only pages 1-2 are available for preview. Some parts have been intentionally blurred.

!
2!
Choose the one best or most appropriate answer
Lectures 1-4. Dr. Philpott
1.!How!did!Edward!Jenner’s!experiment!performed!on!young!James!Phipps!differ!
from!variolation!(the!practice!of!exposing!people!to!material!from!smallpox!scabs)?!
A. Jenner!used!a!killed!form!of!smallpox!rather!than!material!from!smallpox!
scabs!to!inoculate!James!
B. Jenner!thought!that!cowpox!infection!could!protect!from!smallpox.!!He!
inoculated!James!first!with!material!from!cowpox!blisters!and!a!few!weeks!
later!with!material!from!smallpox!scabs!
C. Jenner!inoculated!James!with!the!serum!of!smallpox!survivors!because!he!
thought!smallpox!survivors!contained!a!component!that!would!protect!from!
the!disease!!
D. Variolation!involved!inhalation!of!powdered!material!from!dry!scabs!that!
could!cause!a!potentially!deadly!form!of!respiratory!smallpox.!Jenner!
realized!that!smallpox!inoculation!under!the!skin!was!much!safer!and!
induced!protection!
Ans.!B!
2.!Identify!the!mismatched!scientist:!achievement!pair.!
A. Ilya!Metchnikoff:!main!proponent!of!the!theory!of!humoral!immunity!!
B. Antonie!van!Leeuwenhoek:!discovery!of!microorganisms!
C. Von!Behring!and!Kitasato:!first!demonstration!that!the!serum!of!immunized!
animals!can!transfer!protection!to!diphtheria!
D. Robert!Koch:!developed!protocols!to!grow!bacteria!in!pure!cultures!and!
discovered!the!causal!agents!of!several!infectious!diseases!
Ans.!A!
3.!Louis!Pasteur!made!several!contributions!to!the!progress!of!microbiology.!He!
made!the!discoveries!listed!below!with!the!exception!of:!
A. Mycobacteria+tuberculosis!as!the!causal!agent!of!tuberculosis!
B. Fermentation!as!a!process!caused!by!microorganisms!
C. The!disproval!of!spontaneous!generation!of!microorganisms!
D. The!first!rabies!vaccine!
Ans.!A!
4.!Paul!Ehrlich!theorized!that!antitoxins!interact!with!toxins!through!a!‘lock!and!key’!
type!of!interaction.!He!used!this!analogy!in!reference!to:!
A. The!structural!complementarity!that!allows!an!antigen!to!bind!to!its!specific!
receptor!expressed!on!lymphocytes!
B. The!structural!complementarity!that!allows!a!secreted!antibody!to!bind!to!its!
specific!antigen!in!the!extracellular!environment!
You're Reading a Preview

Unlock to view full version