IMM250H1 Study Guide - Midterm Guide: V(D)J Recombination, Clostridium Difficile Infection, Inflammatory Bowel Disease
Document Summary
Immune system the tissues, cells and molecules involved in protecting the host and responding to foreign antigens primary defence against pathogens. Variolation the inoculation of scab material into the skin of individuals. Reported the concept of immunity after exposure to disease during a plague outbreak. Understand that fever is a mechanism for fighting infection. Suggested contagious particles transmitted disease by direct or indirect contact or even without. The first production of attenuated chicken cholera vaccine. Discovered role of phagocytes in invertebrates (star fish) White blood cells could engulf and destroy harmful bodies such as bacteria. Developed a serum-based therapy for diphtheria and tetanus. Proposed the side-chain theory was that antibodies are naturally occurring macromolecules within the body whose specificity for antigen and complement depends on the presence of certain sterio-chemical configurations. An animal previously infected with tuberculosis organisms is re-infected intra-cutaneously, a local inflammatory reaction marked by necrotic lesions will develop rapidly and heal quickly.