IMM250H1 Final: priming the T cell response

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8 Mar 2011
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adaptive immune response is one of antigen-specific lymphocytes (b and. *memory: ability to respond to the antigen of the individual infected with the same antigen recognition mechanisms of adaptive immunity. variable = can handle a wide range of pathogens/antigens. *cell-mediated immunity: any adaptive immune response in which antigen-specific t cells have the main role. cannot be transferred to a naive recipient with serum antibody. *humoral immunity: antibody-mediated specific immunity made in a humoral response. can be transferred to unimmunized recipients by using immune serum containing specific antibodies adaptive immune responses. generated by clonal selection of lymphocytes (1 lymphocyte sees 1 antigen) distinct from innate and non-adaptive immunity {which are not mediated by clonal selection} vast majority of t cells that have undergone clonal expansion will die during the immune response and leave a small number of memory cells to circulate in the body antigens. at the molecular level, an antigen is characteriz0/-9,-994-0-4:3/,990,3903-binding site of an antibody.

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