LMP299Y1 Study Guide - Midterm Guide: Infection, Leukocytosis, Hypercholesterolemia

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Lecture 1 introduction to the biochemistry of human disease. Dorland"s medical dictionary: definite sickness having a characteristic train of symptoms. Definitive diagnosis usually requires objective evidence of the pathologic process ex. Demonstration of specific biochemical abnormality. Visualization of a tumor by ultrasound imaging. Finding an inflamed appendix at surgery appendicitis inflamed appendix during surgery. Isolation of bacillus/virus infection by bacteria. Medical laboratory services pathology (anatomic), includes: Histology (tissues) and cytology (cells) often microscopic hematology, includes: Diseases of the blood, blood transfusion medicine, and immunology. Various infectious agents: bacteriology, virology, parasitology, mycology biochemistry, or clinical chemistry genetics, includes: Molecular genetics changes in genes. Kidney disease has numerous causes, lab tests can identify which one is the reason. Social role of laboratories impact of disease on society. Mortality: disease that causes death or reduces life expectancy want to live longer. Young people: childbirth and accidents. Middle aged: cardiac disease and strokes. Elderly: cardiac, stroke, cancer, respiratory, mental diseases.

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