MGY377H1 Midterm: Study notes for midterm

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redtermite204

24 Dec 2011

School

UTSG

Department

Molecular Genetics and Microbiology

Course

MGY377H1

Professor

William Navarre

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Document Summary

Ex200 midterm 35 multiple choice same time as lecture. Colonies get bigger and bigger can overrun each other, get smear. Microbes used to make food, protect food from microbes. Certain species have maximum growth rate, cannot be exceeded despite optimal conditions. Stress: e. coli ideal conditions, bacteria can double every twenty minutes, but in real world, grow slower. Antibiotics used to treat clinical disease doesn t kill bacteria, just stop growth and allow immune system to clear. Tuberculosis grow slowly dormancy: 6 months treatment. Fts proteins form divisome ftsz highly conserved and distributed in prokaryotes: also structurally similar to tubulin in human cells, microtubules important for cell shape, transport, cell division microtubules formed by tubulin, similar to bacteria. Ftsz proteins self-assembly at cell midpoint into z ring this serves as scaffold to recruit other divisome proteins recruit machinery to drive division of cell zip!

Related Questions

Letâs assume that under perfect conditions a bacterial cell has a generation time of 20 minutes, infinite access to nutrients and space, no phages or other predators. Any side products for their metabolism disappear instantly and it has access to an unlimited supply of final electron acceptors. â¢ How long until that one cell divided enough time to reach the same mass as planet Earth? How many times does it need to divide to reach this mass? â¢ Earth = 5.97200 Ã 10 27 grams â¢ 1 bacterial cell ~ 1pg = 1x10 -12 grams

Antibiotics kill bacteria and can be an effective treatment forbacterial diseases. Antibiotic resistance is an evolutionaryresponse by the bacteria to an antibiotic, where bacteria are ableto survive and increase in the population if they possess amutation such that the antibiotic is not effective. Then, theantibiotic is less successful against that population of bacteria.The British government has called antibiotic resistance a majornational risk. In this article,Antibiotics Target Gene Expression,the Chief Scientific Officer of ProCarta BioSystems, MichaelMcArthur, discusses a new antibiotic targeting gene expression.

Answer the following four questions based on this article. Besure to put your answers in your own words and number youranswers.

[1 point] What type of molecule is their new antibiotic?

[1 point] What is the mechanism that the antibiotic uses to killspecific bacteria?

{1 point] What prevents the antibiotic from killing humancells?

[1 point] How did they describe how the antibiotic might enterthe bacterial cell?