MGY277H1 Study Guide - Final Guide: Cryptococcus Neoformans, Pneumocystis Jirovecii, Gram Staining
10 Jul 2017
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Know basics of these diseases: salmonella, salmonella enterica causes severe intestinal disease and spread systemically. 1: spastic paralysis (excessive muscle contraction, botulism, most potent neurotoxin inhibits ach release from excitatory neurons to muscles flaccid paralysis (no muscle contraction) Legionella: use type 4 secretion system to colonize and kill amoebae, can survive within macrophages, low spread because has trouble leaving lungs, crystosprodium, causes cryptosporidiosis. Infects intestinal cells and causes severe diarrhea: resistant to chlorine and other disinfectant (hard to eliminate from water, naegleria, primary amebic meningoencephalitis (brain eating amoeba, amoebae cross the nasal mucosa and enter the brain. Invade deep layers of the skin and subcutaneous tissues: normally lives within microbiota but cause disease when they are able to switch between yeast and filamentous form. Histoplasma: histoplasmosis is caused by histoplasma capsulatum, disease resembles the symptoms of tuberculosis. Indicates patient has underlying immunodeficiency: grows inside macrophages, forms granulomas, cryptococcus, cryptococcal meningoencephalitis caused by two strains: cryptococcus neoformans and.
